Ablation of Indian hedgehog in the murine uterus results in decreased cell cycle progression, aberrant epidermal growth factor signaling, and increased estrogen signaling.

Franco, Heather L; Lee, Kevin Y; Broaddus, Russell R; White, Lisa D; Lanske, Beate; Lydon, John P; Jeong, Jae-Wook; DeMayo, Francesco J

Franco, Heather L; Lee, Kevin Y; Broaddus, Russell R; White, Lisa D; Lanske, Beate; Lydon, John P; Jeong, Jae-Wook; DeMayo, Francesco J.

Affiliation

Franco HL; Departments of Molecular and Cellular Biology and Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.

Biol Reprod ; 82(4): 783-90, 2010 Apr.

Article in En | MEDLINE | ID: mdl-20056671

Subject(s)

Cell Cycle/genetics; Epidermal Growth Factor/metabolism; Estradiol/metabolism; Gene Deletion; Hedgehog Proteins/genetics; Animals; Cell Cycle/drug effects; Cell Cycle/physiology; Embryo Implantation/genetics; Epidermal Growth Factor/pharmacology; Epidermal Growth Factor/physiology; Estradiol/pharmacology; Estradiol/physiology; Female; Gene Expression Regulation/drug effects; Genes, cdc/drug effects; Genes, cdc/physiology; Hedgehog Proteins/metabolism; Hedgehog Proteins/physiology; Mice; Mice, Transgenic; Models, Biological; Pregnancy; Signal Transduction/drug effects; Signal Transduction/genetics; Uterus/drug effects; Uterus/metabolism; Uterus/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Cycle / Gene Deletion / Epidermal Growth Factor / Estradiol / Hedgehog Proteins Type of study: Prognostic_studies Limits: Animals / Pregnancy Language: En Journal: Biol Reprod Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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