Capsiate inhibits ultraviolet B-induced skin inflammation by inhibiting Src family kinases and epidermal growth factor receptor signaling.

Lee, Eun-Jung; Jeon, Myung-Shin; Kim, Byung-Dong; Kim, Jeong-Han; Kwon, Young-Guen; Lee, Hyangkyu; Lee, Yun Sang; Yang, Jeong-Hee; Kim, Tae-Yoon

Lee, Eun-Jung; Jeon, Myung-Shin; Kim, Byung-Dong; Kim, Jeong-Han; Kwon, Young-Guen; Lee, Hyangkyu; Lee, Yun Sang; Yang, Jeong-Hee; Kim, Tae-Yoon.

Affiliation

Lee EJ; Laboratory of Dermatology-Immunology, Catholic Research Institute of Medical Science, Catholic University, Seoul 137-040, South Korea.

Free Radic Biol Med ; 48(9): 1133-43, 2010 May 01.

Article in En | MEDLINE | ID: mdl-20123015

Subject(s)

Anti-Inflammatory Agents/pharmacology; Capsaicin/analogs & derivatives; ErbB Receptors/drug effects; Keratinocytes/drug effects; Signal Transduction/drug effects; src-Family Kinases/drug effects; Animals; Blotting, Western; Capsaicin/pharmacology; Cell Line; Cell Survival/drug effects; Cell Survival/radiation effects; Dermatitis/metabolism; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Inflammation/prevention & control; Keratinocytes/metabolism; Keratinocytes/radiation effects; Mice; Neovascularization, Pathologic/drug therapy; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction/radiation effects; Ultraviolet Rays/adverse effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Capsaicin / Signal Transduction / Keratinocytes / Src-Family Kinases / ErbB Receptors / Anti-Inflammatory Agents Limits: Animals / Humans Language: En Journal: Free Radic Biol Med Journal subject: BIOQUIMICA / MEDICINA Year: 2010 Document type: Article Affiliation country: South Korea Country of publication: United States

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