Your browser doesn't support javascript.
loading
Macrocyclic metal complexes derived from 2,6-diaminopyridine and isatin with their antibacterial and spectroscopic studies.
Singh, D P; Malik, Vandna; Kumar, Krishan; Sharma, Chetan; Aneja, K R.
Affiliation
  • Singh DP; Department of Chemistry, National Institute of Technology, Kurukshetra 136119, India. dpsinghchem@yahoo.co.in
Article in En | MEDLINE | ID: mdl-20338803
Condensation reaction of 2,6-diaminopyridine with isatin in the presence of divalent metal ions results in the formation of the macrocyclic complexes of the type [M(C(26)H(16)N(8))X(2)], where M=Co(II), Ni(II), Cu(II), Zn(II), Cd(II) and X=Cl(-), NO(3)(-), CH(3)COO(-). The complexes have been characterized with the aid of elemental analyses, conductance measurements, electronic, NMR, infrared and EPR spectral studies. The lower values of molar conductance indicate them to be non-electrolytes. On the basis of these studies, a six coordinate distorted octahedral geometry in which four nitrogen atoms are suitably placed for coordination towards metal ion, has been proposed for all the complexes. The complexes were tested for their in vitro antibacterial activity. Some of the complexes showed good antibacterial activities against some selected bacterial strains.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Bacteria / Coordination Complexes / Isatin / Anti-Bacterial Agents Language: En Journal: Spectrochim Acta A Mol Biomol Spectrosc Journal subject: BIOLOGIA MOLECULAR Year: 2010 Document type: Article Affiliation country: India Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Bacteria / Coordination Complexes / Isatin / Anti-Bacterial Agents Language: En Journal: Spectrochim Acta A Mol Biomol Spectrosc Journal subject: BIOLOGIA MOLECULAR Year: 2010 Document type: Article Affiliation country: India Country of publication: United kingdom