Correction of a human beta S-globin gene by gene targeting.

Shesely, E G; Kim, H S; Shehee, W R; Papayannopoulou, T; Smithies, O; Popovich, B W

Shesely, E G; Kim, H S; Shehee, W R; Papayannopoulou, T; Smithies, O; Popovich, B W.

Affiliation

Shesely EG; Department of Pathology, University of North Carolina, Chapel Hill 27599-7525.

Proc Natl Acad Sci U S A ; 88(10): 4294-8, 1991 May 15.

Article in En | MEDLINE | ID: mdl-2034673

Subject(s)

Globins/genetics; Hemoglobin, Sickle/genetics; Transfection; Animals; Base Sequence; Cell Line, Transformed; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Expression Regulation; Humans; Hybrid Cells; Leukemia, Erythroblastic, Acute; Lymphocytes; Mice; Molecular Sequence Data; Nucleic Acid Hybridization; Polymerase Chain Reaction; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Globins / Hemoglobin, Sickle / Transfection Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 1991 Document type: Article Country of publication: United States

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