Inhibition of apoptotic cell death by ghrelin improves functional recovery after spinal cord injury.

Lee, Jee Y; Chung, Hyunju; Yoo, Young S; Oh, Young J; Oh, Tae H; Park, Seungjoon; Yune, Tae Y

Lee, Jee Y; Chung, Hyunju; Yoo, Young S; Oh, Young J; Oh, Tae H; Park, Seungjoon; Yune, Tae Y.

Affiliation

Lee JY; Neurodegeneration Control Research Center, and Age-Related and Brain Diseases Research Center, Department of Biochemistry and Molecular Biology and Age-Related and Brain Diseases Research Center, School of Medicine, Kyung Hee University, Medical Building, Seoul 130-701, Korea.

Endocrinology ; 151(8): 3815-26, 2010 Aug.

Article in En | MEDLINE | ID: mdl-20444938

Subject(s)

Apoptosis/drug effects; Ghrelin/pharmacology; Recovery of Function/drug effects; Spinal Cord Injuries/rehabilitation; Animals; Caspase 3/metabolism; Caspase Inhibitors; Cell Death/drug effects; Cytochromes c/metabolism; Down-Regulation/drug effects; Ghrelin/therapeutic use; Male; Mice; Neurons/drug effects; Neurons/pathology; Oligodendroglia/drug effects; Oligodendroglia/pathology; Rats; Rats, Sprague-Dawley; Spinal Cord/drug effects; Spinal Cord/pathology; Spinal Cord Injuries/drug therapy; Spinal Cord Injuries/metabolism; Spinal Cord Injuries/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord Injuries / Apoptosis / Recovery of Function / Ghrelin Type of study: Evaluation_studies Limits: Animals Language: En Journal: Endocrinology Year: 2010 Document type: Article Country of publication: United States

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