Host genetics in granuloma formation: human-like lung pathology in mice with reciprocal genetic susceptibility to M. tuberculosis and M. avium.

Kondratieva, Elena; Logunova, Nadya; Majorov, Konstantin; Averbakh, Mikhail; Apt, Alexander

Kondratieva, Elena; Logunova, Nadya; Majorov, Konstantin; Averbakh, Mikhail; Apt, Alexander.

Affiliation

Kondratieva E; Laboratory for Immunogenetics, Central Institute for Tuberculosis, Moscow, Russia.

PLoS One ; 5(5): e10515, 2010 May 06.

Article in En | MEDLINE | ID: mdl-20463893

Subject(s)

Genetic Predisposition to Disease; Granuloma/microbiology; Granuloma/pathology; Host-Pathogen Interactions/genetics; Lung/pathology; Mycobacterium avium/physiology; Mycobacterium tuberculosis/physiology; Animals; Chemokines/genetics; Chemokines/metabolism; Gene Expression Regulation; Humans; Immunity, Innate/genetics; Inflammation/pathology; Leukocyte Count; Lung/microbiology; Mice; Mice, Inbred C57BL; Neutrophils/pathology; Phenotype; Tuberculosis/genetics; Tuberculosis/microbiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Predisposition to Disease / Host-Pathogen Interactions / Granuloma / Lung / Mycobacterium avium / Mycobacterium tuberculosis Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2010 Document type: Article Affiliation country: RUSSIA

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