Serum response factor is an essential transcription factor in megakaryocytic maturation.

Halene, Stephanie; Gao, Yuan; Hahn, Katherine; Massaro, Stephanie; Italiano, Joseph E; Schulz, Vincent; Lin, Sharon; Kupfer, Gary M; Krause, Diane S

Halene, Stephanie; Gao, Yuan; Hahn, Katherine; Massaro, Stephanie; Italiano, Joseph E; Schulz, Vincent; Lin, Sharon; Kupfer, Gary M; Krause, Diane S.

Affiliation

Halene S; Department of Internal Medicine and Yale Cancer Center, Section of Hematology, 333 Cedar Street, New Haven, CT 06520, USA. stephanie.halene@yale.edu

Blood ; 116(11): 1942-50, 2010 Sep 16.

Article in En | MEDLINE | ID: mdl-20525922

Subject(s)

Blood Platelets/metabolism; Megakaryocytes/metabolism; Serum Response Factor/metabolism; Transcription Factors/metabolism; Animals; Bleeding Time; Blood Platelets/cytology; Bone Marrow Cells/cytology; Bone Marrow Cells/metabolism; Cell Differentiation; Cell Lineage; Cells, Cultured; Cytoskeleton/metabolism; Cytoskeleton/ultrastructure; Female; Flow Cytometry; Gene Expression Profiling; Luminescent Proteins/genetics; Luminescent Proteins/metabolism; Male; Megakaryocytes/cytology; Megakaryocytes/ultrastructure; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy, Electron, Transmission; Platelet Count; Platelet Factor 4/genetics; Platelet Factor 4/metabolism; Reverse Transcriptase Polymerase Chain Reaction; Serum Response Factor/genetics; Thrombocytopenia/genetics; Thrombocytopenia/metabolism; Thrombocytopenia/pathology; Transcription Factors/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Blood Platelets / Megakaryocytes / Serum Response Factor Language: En Journal: Blood Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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