Anti-tumor effects by a synthetic chalcone compound is mediated by c-Myc-mediated reactive oxygen species production.

Kim, Tae-Hee; Seo, Woo Duck; Ryu, Hyung Won; Seo, Haeng Ran; Jin, Yeung Bae; Lee, Minyoung; Ji, Young-Hoon; Park, Ki Hun; Lee, Yun-Sil

Kim, Tae-Hee; Seo, Woo Duck; Ryu, Hyung Won; Seo, Haeng Ran; Jin, Yeung Bae; Lee, Minyoung; Ji, Young-Hoon; Park, Ki Hun; Lee, Yun-Sil.

Affiliation

Kim TH; Division of Radiation Effects, Korea Institute of Radiological and Medical Sciences, 215-4 Gongneung-Dong, Nowon-Ku, Seoul 139-706, Republic of Korea.

Chem Biol Interact ; 188(1): 111-8, 2010 Oct 06.

Article in En | MEDLINE | ID: mdl-20620131

Subject(s)

Antineoplastic Agents/pharmacology; Chalcones/pharmacology; Proto-Oncogene Proteins c-myc/metabolism; Reactive Oxygen Species/metabolism; Animals; Blotting, Western; Cell Line, Tumor; Flow Cytometry; Humans; Mice; Mice, Nude; Neoplasm Transplantation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins c-myc / Reactive Oxygen Species / Chalcones / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Chem Biol Interact Year: 2010 Document type: Article Country of publication: Ireland

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