Autophagy plays an important role in sunitinib-mediated cell death in H9c2 cardiac muscle cells.

Zhao, Yuqin; Xue, Tao; Yang, Xiaochun; Zhu, Hong; Ding, Xiaofei; Lou, Liming; Lu, Wei; Yang, Bo; He, Qiaojun

Zhao, Yuqin; Xue, Tao; Yang, Xiaochun; Zhu, Hong; Ding, Xiaofei; Lou, Liming; Lu, Wei; Yang, Bo; He, Qiaojun.

Affiliation

Zhao Y; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

Toxicol Appl Pharmacol ; 248(1): 20-7, 2010 Oct 01.

Article in En | MEDLINE | ID: mdl-20637791

Subject(s)

Antineoplastic Agents/toxicity; Autophagy/drug effects; Indoles/toxicity; Myocytes, Cardiac/drug effects; Pyrroles/toxicity; Animals; Apoptosis/drug effects; Apoptosis Regulatory Proteins/genetics; Beclin-1; Cell Line; Cell Proliferation/drug effects; Microtubule-Associated Proteins/drug effects; Microtubule-Associated Proteins/metabolism; Myocytes, Cardiac/metabolism; RNA Interference; Rats; Sunitinib

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Autophagy / Myocytes, Cardiac / Indoles / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2010 Document type: Article Affiliation country: China Country of publication: United States

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