Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-Î´ (Î´-PKC).

Kilpatrick, Laurie E; Standage, Stephen W; Li, Haiying; Raj, Nichelle R; Korchak, Helen M; Wolfson, Marla R; Deutschman, Clifford S

Kilpatrick, Laurie E; Standage, Stephen W; Li, Haiying; Raj, Nichelle R; Korchak, Helen M; Wolfson, Marla R; Deutschman, Clifford S.

Affiliation

Kilpatrick LE; Temple University School of Medicine, 3307 North Broad St., PAH-206, Philadelphia, PA 19140, USA. laurie.kilpatrick@temple.edu

J Leukoc Biol ; 89(1): 3-10, 2011 Jan.

Article in En | MEDLINE | ID: mdl-20724665

Subject(s)

Lung Injury/etiology; Lung Injury/prevention & control; Protein Kinase C-delta/antagonists & inhibitors; Protein Kinase Inhibitors/pharmacology; Sepsis/complications; Animals; Bronchoalveolar Lavage Fluid; Chemokine CXCL1/metabolism; Chemokine CXCL2/metabolism; Diagnostic Imaging; Lung/drug effects; Lung/enzymology; Lung/pathology; Lung Injury/drug therapy; Lung Injury/pathology; Male; Peptides/administration & dosage; Peptides/pharmacology; Peptides/therapeutic use; Phosphorylation/drug effects; Phosphothreonine/metabolism; Protein Kinase C-delta/metabolism; Protein Kinase Inhibitors/administration & dosage; Protein Kinase Inhibitors/therapeutic use; Rats; Rats, Sprague-Dawley; Sepsis/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sepsis / Protein Kinase Inhibitors / Protein Kinase C-delta / Lung Injury Type of study: Diagnostic_studies Limits: Animals Language: En Journal: J Leukoc Biol Year: 2011 Document type: Article Affiliation country: United States

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