Cytotoxic and genotoxic effects of cylindrospermopsin in mice treated by gavage or intraperitoneal injection.

Bazin, Emmanuelle; Huet, Sylvie; Jarry, Gérard; Le Hégarat, Ludovic; Munday, John S; Humpage, Andrew R; Fessard, Valérie

Bazin, Emmanuelle; Huet, Sylvie; Jarry, Gérard; Le Hégarat, Ludovic; Munday, John S; Humpage, Andrew R; Fessard, Valérie.

Affiliation

Bazin E; Agence Française de Sécurité Sanitaire des Aliments, Unité de Toxicologie Génétique des Contaminants Alimentaires, BP 90 203, 35302 Fougères Cedex, France.

Environ Toxicol ; 27(5): 277-84, 2012 May.

Article in En | MEDLINE | ID: mdl-20725938

Subject(s)

Mutagens/toxicity; Uracil/analogs & derivatives; Administration, Oral; Alkaloids; Animals; Bacterial Toxins/administration & dosage; Bacterial Toxins/toxicity; Bone Marrow/drug effects; Bone Marrow/pathology; Comet Assay; Cyanobacteria; Cyanobacteria Toxins; DNA Breaks; DNA Damage; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Kidney/drug effects; Kidney/pathology; Liver/drug effects; Liver/pathology; Male; Marine Toxins/administration & dosage; Marine Toxins/toxicity; Methyl Methanesulfonate/toxicity; Mice; Microcystins/administration & dosage; Microcystins/toxicity; Micronucleus Tests; Mutagens/administration & dosage; Uracil/administration & dosage; Uracil/toxicity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uracil / Mutagens Limits: Animals Language: En Journal: Environ Toxicol Journal subject: SAUDE AMBIENTAL / TOXICOLOGIA Year: 2012 Document type: Article Affiliation country: France Country of publication: United States

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