Endogenous sulfur dioxide protects against isoproterenol-induced myocardial injury and increases myocardial antioxidant capacity in rats.

Liang, Yinfang; Liu, Die; Ochs, Todd; Tang, Chaoshu; Chen, Stella; Zhang, Suqing; Geng, Bin; Jin, Hongfang; Du, Junbao

Liang, Yinfang; Liu, Die; Ochs, Todd; Tang, Chaoshu; Chen, Stella; Zhang, Suqing; Geng, Bin; Jin, Hongfang; Du, Junbao.

Affiliation

Liang Y; Department of Pediatrics, Peking University First Hospital, Beijing, PR China.

Lab Invest ; 91(1): 12-23, 2011 Jan.

Article in En | MEDLINE | ID: mdl-20733562

Subject(s)

Antioxidants/metabolism; Cardiomyopathies/metabolism; Myocardium/metabolism; Sulfur Dioxide/metabolism; Animals; Aspartate Aminotransferases/genetics; Aspartate Aminotransferases/metabolism; Cardiomyopathies/chemically induced; Cardiomyopathies/prevention & control; Gene Expression; Glutathione Peroxidase/genetics; Heart/drug effects; Heart/physiopathology; Hydrogen Peroxide/metabolism; Isoenzymes/genetics; Isoenzymes/metabolism; Isoproterenol; Male; Microscopy, Electron, Transmission; Mitochondria, Heart/drug effects; Mitochondria, Heart/ultrastructure; Myocardium/pathology; Myocardium/ultrastructure; Oxidants/metabolism; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sulfates/metabolism; Sulfates/pharmacology; Sulfites/metabolism; Sulfites/pharmacology; Superoxide Dismutase/genetics; Superoxides/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfur Dioxide / Cardiomyopathies / Myocardium / Antioxidants Limits: Animals Language: En Journal: Lab Invest Year: 2011 Document type: Article Country of publication: United States

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