The M-channel blocker linopirdine is an agonist of the capsaicin receptor TRPV1.

Neacsu, Cristian; Babes, Alexandru

Neacsu, Cristian; Babes, Alexandru.

Affiliation

Neacsu C; Department of Anatomy, Physiology and Biophysics, Faculty of Biology, University of Bucharest, Romania.

J Pharmacol Sci ; 114(3): 332-40, 2010.

Article in En | MEDLINE | ID: mdl-21099148

Subject(s)

Capsaicin/metabolism; Ganglia, Spinal/drug effects; Indoles/pharmacology; KCNQ Potassium Channels/antagonists & inhibitors; Nociceptors/metabolism; Pyridines/pharmacology; TRPV Cation Channels/agonists; Animals; Calcium/metabolism; Capsaicin/analogs & derivatives; Capsaicin/pharmacology; Ganglia, Spinal/cytology; Ganglia, Spinal/metabolism; HEK293 Cells; Hot Temperature; Humans; Indoles/metabolism; KCNQ Potassium Channels/metabolism; Neurons/metabolism; Pyridines/metabolism; Rats; Rats, Wistar; TRPV Cation Channels/antagonists & inhibitors; TRPV Cation Channels/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Nociceptors / Capsaicin / KCNQ Potassium Channels / TRPV Cation Channels / Ganglia, Spinal / Indoles Limits: Animals / Humans Language: En Journal: J Pharmacol Sci Journal subject: FARMACOLOGIA Year: 2010 Document type: Article Affiliation country: Romania

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