FK962 and donepezil act synergistically to improve cognition in rats: potential as an add-on therapy for Alzheimer's disease.

McCarthy, Alun D; Owens, Ian J; Bansal, Aruna T; McTighe, Stephanie M; Bussey, Timothy J; Saksida, Lisa M

McCarthy, Alun D; Owens, Ian J; Bansal, Aruna T; McTighe, Stephanie M; Bussey, Timothy J; Saksida, Lisa M.

Affiliation

McCarthy AD; PGXIS Ltd., Aston Court, Kingsmead Business Park, Frederick Place, High Wycombe, Bucks HP11 1LA, UK. alun.mccarthy@pgxis.com

Pharmacol Biochem Behav ; 98(1): 76-80, 2011 Mar.

Article in En | MEDLINE | ID: mdl-21130801

Subject(s)

Benzamides/administration & dosage; Cognition/drug effects; Indans/administration & dosage; Nootropic Agents/administration & dosage; Piperidines/administration & dosage; Alzheimer Disease/drug therapy; Animals; Cholinesterase Inhibitors/administration & dosage; Discrimination Learning/drug effects; Donepezil; Dose-Response Relationship, Drug; Drug Synergism; Humans; Male; Models, Animal; Photic Stimulation; Rats; Reward

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Benzamides / Cognition / Nootropic Agents / Indans Limits: Animals / Humans / Male Language: En Journal: Pharmacol Biochem Behav Year: 2011 Document type: Article Affiliation country: United kingdom Country of publication: United States

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