Influence of preparation method on polynucleotide conformation and pharmacological activity of lipoplex.

Saheki, Akira; Fukui, Yoshiharu; Hoshi, Yuji; Fukui, Hiroshi; Seki, Junzo; Tamai, Ikumi

Saheki, Akira; Fukui, Yoshiharu; Hoshi, Yuji; Fukui, Hiroshi; Seki, Junzo; Tamai, Ikumi.

Affiliation

Saheki A; Research & Development Division, Nippon Shinyaku Co. Ltd., 14 Nishinosho-Monguchi-cho Kisshoin, Minami-ku, Kyoto 601-8550, Japan. a.saheki@po.nippon-shinyaku.co.jp

Int J Pharm ; 406(1-2): 117-21, 2011 Mar 15.

Article in En | MEDLINE | ID: mdl-21184816

Subject(s)

Poly C/chemistry; Poly C/pharmacology; Poly I/chemistry; Poly I/pharmacology; Technology, Pharmaceutical/methods; Cell Line, Tumor; Cell Proliferation/drug effects; Circular Dichroism; Fluorescence Resonance Energy Transfer; Humans; Hydrogen-Ion Concentration; Lecithins/chemistry; Liposomes; Nucleic Acid Conformation; Particle Size; Solutions

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Poly C / Poly I / Technology, Pharmaceutical Limits: Humans Language: En Journal: Int J Pharm Year: 2011 Document type: Article Affiliation country: Japan Country of publication: Netherlands

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