The pronociceptive effect of proteinase-activated receptor-4 stimulation in rat knee joints is dependent on mast cell activation.

Russell, Fiona A; Zhan, Shu; Dumas, Aline; Lagarde, Stéphanie; Pouliot, Marc; McDougall, Jason J

Russell, Fiona A; Zhan, Shu; Dumas, Aline; Lagarde, Stéphanie; Pouliot, Marc; McDougall, Jason J.

Affiliation

Russell FA; Department of Physiology and Pharmacology, University of Calgary, 3330 Hospital Drive NW, Calgary, Alta., Canada T2N 4N1 Centre de Recherche en Rhumatologie et Immunologie du CHUQ, Department of Microbiology-Infectiology and Immunology, Faculty of Medicine, Laval University, Que., Canada.

Pain ; 152(2): 354-360, 2011 Feb.

Article in En | MEDLINE | ID: mdl-21238854

Subject(s)

Arthralgia/metabolism; Knee Joint/metabolism; Mast Cells/metabolism; Nociceptors/physiology; Oligopeptides/metabolism; Receptors, Thrombin/metabolism; Animals; Arthralgia/pathology; Knee Joint/innervation; Knee Joint/pathology; Male; Mast Cells/drug effects; Mast Cells/pathology; Nociceptors/drug effects; Oligopeptides/physiology; Rats; Rats, Wistar; Receptors, Thrombin/physiology; Synovial Membrane/drug effects; Synovial Membrane/metabolism; Synovial Membrane/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Nociceptors / Receptors, Thrombin / Arthralgia / Knee Joint / Mast Cells Limits: Animals Language: En Journal: Pain Year: 2011 Document type: Article Affiliation country: Canada Country of publication: United States

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