Comparison of effects of alcaftadine and olopatadine on conjunctival epithelium and eosinophil recruitment in a murine model of allergic conjunctivitis.

Ono, Santa J; Lane, Keith

Ono, Santa J; Lane, Keith.

Affiliation

Ono SJ; Emory University School of Medicine and Emory Eye Center, Dobbs Ocular Immunology Laboratories, Atlanta, GA, USA.

Drug Des Devel Ther ; 5: 77-84, 2011 Feb 08.

Article in En | MEDLINE | ID: mdl-21340041

Subject(s)

Anti-Allergic Agents/pharmacokinetics; Benzazepines/pharmacology; Conjunctivitis, Allergic/drug therapy; Dibenzoxepins/pharmacology; Imidazoles/pharmacology; Animals; Anti-Allergic Agents/administration & dosage; Benzazepines/administration & dosage; Conjunctiva/drug effects; Conjunctiva/metabolism; Dibenzoxepins/administration & dosage; Disease Models, Animal; Eosinophils/drug effects; Eosinophils/metabolism; Epithelium/drug effects; Epithelium/metabolism; Gene Expression Regulation/drug effects; Imidazoles/administration & dosage; Membrane Proteins/genetics; Mice; Mice, Inbred BALB C; Olopatadine Hydrochloride; Phosphoproteins/genetics; Tight Junctions/drug effects; Tight Junctions/metabolism; Time Factors; Zonula Occludens-1 Protein

Key words

alcaftadine; ocular allergy; olopatadine

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzazepines / Conjunctivitis, Allergic / Anti-Allergic Agents / Dibenzoxepins / Imidazoles Type of study: Prognostic_studies Limits: Animals Language: En Journal: Drug Des Devel Ther Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2011 Document type: Article Affiliation country: United States Country of publication: New Zealand

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