Functional coupling between metabotropic glutamate receptors and G-proteins in rat cerebral cortex assessed by guanosine-5'-O-(3-[(35)S]thio)triphosphate binding assay.

Odagaki, Yuji; Kinoshita, Masakazu; Toyoshima, Ryoichi

Odagaki, Yuji; Kinoshita, Masakazu; Toyoshima, Ryoichi.

Affiliation

Odagaki Y; Department of Psychiatry, Faculty of Medicine, Saitama Medical University, Moroyama-machi, Iruma-gun, Japan. odagaki@saitama-med.ac.jp

Basic Clin Pharmacol Toxicol ; 109(3): 175-85, 2011 Sep.

Article in En | MEDLINE | ID: mdl-21443596

Subject(s)

Cerebral Cortex/metabolism; GTP-Binding Protein alpha Subunits, Gi-Go/metabolism; Guanosine 5'-O-(3-Thiotriphosphate)/metabolism; Receptors, Metabotropic Glutamate/metabolism; Animals; Binding, Competitive; Cell Membrane/drug effects; Cell Membrane/metabolism; Cerebral Cortex/drug effects; Dose-Response Relationship, Drug; Ethylmaleimide/pharmacology; In Vitro Techniques; Male; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate/agonists; Sulfur Radioisotopes; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cerebral Cortex / Guanosine 5'-O-(3-Thiotriphosphate) / Receptors, Metabotropic Glutamate / GTP-Binding Protein alpha Subunits, Gi-Go Limits: Animals Language: En Journal: Basic Clin Pharmacol Toxicol Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2011 Document type: Article Affiliation country: Japan

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