A coordinated synthesis and conjugation strategy for the preparation of homogeneous glycoconjugate vaccine candidates.

Grayson, Elizabeth J; Bernardes, Gonçalo J L; Chalker, Justin M; Boutureira, Omar; Koeppe, Julia R; Davis, Benjamin G

Grayson, Elizabeth J; Bernardes, Gonçalo J L; Chalker, Justin M; Boutureira, Omar; Koeppe, Julia R; Davis, Benjamin G.

Affiliation

Grayson EJ; Department of Chemistry, University of Durham, South Road, Durham DH1 3LE, UK.

Angew Chem Int Ed Engl ; 50(18): 4127-32, 2011 Apr 26.

Article in En | MEDLINE | ID: mdl-21455919

Subject(s)

Glycoconjugates/chemical synthesis; Vaccines, Conjugate/chemistry; Adjuvants, Immunologic; Disulfides/chemistry; Glycoconjugates/chemistry; Klebsiella pneumoniae/immunology; Klebsiella pneumoniae/metabolism; O Antigens/chemistry; Oligosaccharides/chemistry; Structure-Activity Relationship; Subtilisins/chemistry; Vaccines, Conjugate/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycoconjugates / Vaccines, Conjugate Language: En Journal: Angew Chem Int Ed Engl Year: 2011 Document type: Article Affiliation country: United kingdom Country of publication: Germany

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