Using network properties to predict disease dynamics on human contact networks.
Proc Biol Sci
; 278(1724): 3544-50, 2011 Dec 07.
Article
in En
| MEDLINE
| ID: mdl-21525056
Recent studies have increasingly turned to graph theory to model more realistic contact structures that characterize disease spread. Because of the computational demands of these methods, many researchers have sought to use measures of network structure to modify analytically tractable differential equation models. Several of these studies have focused on the degree distribution of the contact network as the basis for their modifications. We show that although degree distribution is sufficient to predict disease behaviour on very sparse or very dense human contact networks, for intermediate density networks we must include information on clustering and path length to accurately predict disease behaviour. Using these three metrics, we were able to explain more than 98 per cent of the variation in endemic disease levels in our stochastic simulations.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Contact Tracing
/
Disease Transmission, Infectious
/
Models, Theoretical
Type of study:
Prognostic_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Proc Biol Sci
Journal subject:
BIOLOGIA
Year:
2011
Document type:
Article
Affiliation country:
United States
Country of publication:
United kingdom