Crystal structure of Serratia fonticola Sfh-I: activation of the nucleophile in mono-zinc metallo-ß-lactamases.

Fonseca, Fátima; Bromley, Elizabeth H C; Saavedra, Maria José; Correia, António; Spencer, James

Fonseca, Fátima; Bromley, Elizabeth H C; Saavedra, Maria José; Correia, António; Spencer, James.

Affiliation

Fonseca F; Center for Environmental and Marine Studies and Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal. ffonseca@ua.pt

J Mol Biol ; 411(5): 951-9, 2011 Sep 02.

Article in En | MEDLINE | ID: mdl-21762699

Subject(s)

Serratia/enzymology; Zinc/metabolism; beta-Lactamases/chemistry; beta-Lactamases/metabolism; Aeromonas hydrophila/enzymology; Asparagine/chemistry; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Hydrolysis; Models, Molecular; Protein Binding; Protein Conformation; Substrate Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Serratia / Zinc / Beta-Lactamases Language: En Journal: J Mol Biol Year: 2011 Document type: Article Affiliation country: Portugal Country of publication: Netherlands

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