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Fresh-frozen human bone allograft in vertical ridge augmentation: clinical and tomographic evaluation of bone formation and resorption.
Macedo, Luis Guilherme Scavone; Mazzucchelli-Cosmo, Luiz Antonio; Macedo, Nelson Luiz; Monteiro, Adriana Socorro Ferreira; Sendyk, Wilson Roberto.
Affiliation
  • Macedo LG; Department of Dental Materials and Prosthesis, São Paulo State University, UNESP, São José dos Campos Dental School, São Paulo, Brazil.
Cell Tissue Bank ; 13(4): 577-86, 2012 Dec.
Article in En | MEDLINE | ID: mdl-21811779
The aim of the current study is to evaluate fresh-frozen human bone allografts (FHBAs) used in vertical ridge augmentation clinically and by computed tomography, and to analyze the resulting bone formation and graft resorption. Sixteen FHBAs were grafted in the maxillae and mandibles of 9 patients. The FHBAs, which were provided by the Musculoskeletal Tissue Bank of Marilia Hospital (Unioss), were frozen at -80°C. After 7 months, dental implants were placed and bone parameters were evaluated. Vertical bone formation was measured by computerized tomography before (T0) and at 7 months (T1) after the surgical procedure. Bone graft resorption was measured clinically from a landmark screw head using a periodontal probe. The results were analyzed by Student's t-test. Significant differences existed in the bone formation values at T0 and T1, with an average change of 4.03 ± 1.69 mm. Bone graft resorption values were 1.0 ± 0.82 mm (20%). Implants were placed with varying insertion torque values (35-45 Ncm), and achieved primary stability. This study demonstrates that FHBAs promote satisfactory vertical bone formation with a low resorption rates, good density, and primary implant stability.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteogenesis / Bone Resorption / Bone Transplantation Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Cell Tissue Bank Journal subject: HISTOLOGIA / TRANSPLANTE Year: 2012 Document type: Article Affiliation country: Brazil Country of publication: Netherlands

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteogenesis / Bone Resorption / Bone Transplantation Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Cell Tissue Bank Journal subject: HISTOLOGIA / TRANSPLANTE Year: 2012 Document type: Article Affiliation country: Brazil Country of publication: Netherlands