Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.

Dawlaty, Meelad M; Ganz, Kibibi; Powell, Benjamin E; Hu, Yueh-Chiang; Markoulaki, Styliani; Cheng, Albert W; Gao, Qing; Kim, Jongpil; Choi, Sang-Woon; Page, David C; Jaenisch, Rudolf

Dawlaty, Meelad M; Ganz, Kibibi; Powell, Benjamin E; Hu, Yueh-Chiang; Markoulaki, Styliani; Cheng, Albert W; Gao, Qing; Kim, Jongpil; Choi, Sang-Woon; Page, David C; Jaenisch, Rudolf.

Affiliation

Dawlaty MM; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.

Cell Stem Cell ; 9(2): 166-75, 2011 Aug 05.

Article in En | MEDLINE | ID: mdl-21816367

Subject(s)

DNA-Binding Proteins/deficiency; DNA-Binding Proteins/metabolism; Embryonic Development; Pluripotent Stem Cells/metabolism; Proto-Oncogene Proteins/deficiency; Proto-Oncogene Proteins/metabolism; 5-Methylcytosine/analogs & derivatives; Animals; Animals, Newborn; Body Size; Cytosine/analogs & derivatives; Cytosine/metabolism; DNA Methylation/genetics; Embryo, Mammalian/metabolism; Embryonic Development/genetics; Embryonic Stem Cells/cytology; Embryonic Stem Cells/metabolism; Female; Fertility; Gene Expression Regulation, Developmental; Gene Knockout Techniques; Genetic Complementation Test; Mice; Mice, Inbred C57BL; Pluripotent Stem Cells/cytology; Tetraploidy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins / Pluripotent Stem Cells / Embryonic Development / DNA-Binding Proteins Limits: Animals Language: En Journal: Cell Stem Cell Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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