An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice.

Mandrekar, Pranoti; Ambade, Aditya; Lim, Arlene; Szabo, Gyongyi; Catalano, Donna

Mandrekar, Pranoti; Ambade, Aditya; Lim, Arlene; Szabo, Gyongyi; Catalano, Donna.

Affiliation

Mandrekar P; Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA. pranoti.mandrekar@umassmed.edu

Hepatology ; 54(6): 2185-97, 2011 Dec.

Article in En | MEDLINE | ID: mdl-21826694

Subject(s)

Chemokine CCL2/physiology; Cytokines/physiology; Fatty Liver, Alcoholic/physiopathology; Liver Diseases, Alcoholic/physiopathology; Liver/metabolism; Receptors, CCR2/physiology; Acyl-CoA Oxidase/metabolism; Animals; Carnitine O-Palmitoyltransferase/metabolism; Cell Line, Tumor; Chemokine CCL2/deficiency; Female; Hepatocytes/drug effects; Hepatocytes/metabolism; Humans; Kupffer Cells/drug effects; Kupffer Cells/metabolism; Lipopolysaccharides; Liver Diseases, Alcoholic/prevention & control; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Peroxisome Proliferator-Activated Receptors/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytokines / Chemokine CCL2 / Receptors, CCR2 / Fatty Liver, Alcoholic / Liver / Liver Diseases, Alcoholic Limits: Animals / Female / Humans Language: En Journal: Hepatology Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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