Oncostatin M decreases interleukin-1 ß secretion by human synovial fibroblasts and attenuates an acute inflammatory reaction in vivo.

Dumas, Aline; Lagarde, Stéphanie; Laflamme, Cynthia; Pouliot, Marc

Dumas, Aline; Lagarde, Stéphanie; Laflamme, Cynthia; Pouliot, Marc.

Affiliation

Dumas A; Centre de Recherche en Rhumatologie et Immunologie du CHUQ, and Department of Microbiology-Infectiology and Immunology, Faculty of Medicine, Laval University, Quebec City, QC, Canada.

J Cell Mol Med ; 16(6): 1274-85, 2012 Jun.

Article in En | MEDLINE | ID: mdl-21854541

Subject(s)

Fibroblasts/drug effects; Inflammation/drug therapy; Interleukin-1beta/metabolism; Oncostatin M/metabolism; Synovial Fluid/drug effects; Animals; Cells, Cultured; Chemokine CCL2/genetics; Chemokine CCL2/metabolism; Gene Expression Profiling; Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology; Humans; Inflammation/pathology; Interleukin-1beta/genetics; Interleukin-6/genetics; Interleukin-6/metabolism; Interleukin-8/genetics; Interleukin-8/metabolism; Leukemia Inhibitory Factor/genetics; Leukemia Inhibitory Factor/metabolism; Lipopolysaccharides/pharmacology; Male; Mice; Real-Time Polymerase Chain Reaction; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Signal Transduction; Synovial Fluid/cytology; Synovial Fluid/metabolism; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synovial Fluid / Interleukin-1beta / Oncostatin M / Fibroblasts / Inflammation Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2012 Document type: Article Affiliation country: Canada Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google