MyD88-dependent production of IL-17F is modulated by the anaphylatoxin C5a via the Akt signaling pathway.

Bosmann, Markus; Patel, Vinay R; Russkamp, Norman F; Pache, Florence; Zetoune, Firas S; Sarma, J Vidya; Ward, Peter A

Bosmann, Markus; Patel, Vinay R; Russkamp, Norman F; Pache, Florence; Zetoune, Firas S; Sarma, J Vidya; Ward, Peter A.

Affiliation

Bosmann M; Department of Pathology, The University of Michigan Medical School, 1301 Catherine Rd., Ann Arbor, MI 48109-5602, USA.

FASEB J ; 25(12): 4222-32, 2011 Dec.

Article in En | MEDLINE | ID: mdl-21859896

Subject(s)

Complement C5a/metabolism; Interleukin-17/biosynthesis; Myeloid Differentiation Factor 88/metabolism; Proto-Oncogene Proteins c-akt/metabolism; Animals; Complement Activation; Endotoxemia/immunology; Endotoxemia/metabolism; Immunity, Innate; Interleukin-17/genetics; Macrophages, Peritoneal/immunology; Macrophages, Peritoneal/metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88/deficiency; Myeloid Differentiation Factor 88/genetics; RNA, Messenger/genetics; RNA, Messenger/metabolism; Signal Transduction; Toll-Like Receptor 4/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Complement C5a / Interleukin-17 / Proto-Oncogene Proteins c-akt / Myeloid Differentiation Factor 88 Type of study: Prognostic_studies Limits: Animals Language: En Journal: FASEB J Journal subject: BIOLOGIA / FISIOLOGIA Year: 2011 Document type: Article Affiliation country: United States Country of publication: United States

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