Histone deacetylase inhibitors reverse CpG methylation by regulating DNMT1 through ERK signaling.

Sarkar, Sibaji; Abujamra, Ana L; Loew, Jenny E; Forman, Lora W; Perrine, Susan P; Faller, Douglas V

Sarkar, Sibaji; Abujamra, Ana L; Loew, Jenny E; Forman, Lora W; Perrine, Susan P; Faller, Douglas V.

Affiliation

Sarkar S; Cancer Center, Boston University School of Medicine, Boston, MA 02118, USA.

Anticancer Res ; 31(9): 2723-32, 2011 Sep.

Article in En | MEDLINE | ID: mdl-21868513

Subject(s)

CpG Islands/drug effects; DNA (Cytosine-5-)-Methyltransferases/metabolism; DNA Methylation/drug effects; Extracellular Signal-Regulated MAP Kinases/metabolism; Histone Deacetylase Inhibitors/pharmacology; Signal Transduction; Cell Cycle/drug effects; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; Humans; Male; Polymerase Chain Reaction; Prostatic Neoplasms/genetics; Prostatic Neoplasms/metabolism; Prostatic Neoplasms/pathology

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / CpG Islands / DNA Methylation / Extracellular Signal-Regulated MAP Kinases / DNA (Cytosine-5-)-Methyltransferases / Histone Deacetylase Inhibitors Limits: Humans / Male Language: En Journal: Anticancer Res Year: 2011 Document type: Article Affiliation country: United States Country of publication: Greece

Search on Google

Add to My VHL

XML

PubMed Links