Moracenin D from Mori Cortex radicis protects SH-SY5Y cells against dopamine-induced cell death by regulating nurr1 and &#945;-synuclein expression.

Ham, Ahrom; Lee, Hak Ju; Hong, Seong Su; Lee, Dongho; Mar, Woongchon

Moracenin D from Mori Cortex radicis protects SH-SY5Y cells against dopamine-induced cell death by regulating nurr1 and α-synuclein expression.

Ham, Ahrom; Lee, Hak Ju; Hong, Seong Su; Lee, Dongho; Mar, Woongchon.

Affiliation

Ham A; Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 151-742, Korea.

Phytother Res ; 26(4): 620-4, 2012 Apr.

Article in En | MEDLINE | ID: mdl-21936000

Subject(s)

Cell Death; Dopamine/adverse effects; Gene Expression Regulation, Neoplastic; Neuroprotective Agents/pharmacology; Nuclear Receptor Subfamily 4, Group A, Member 2/metabolism; alpha-Synuclein/metabolism; Benzofurans/pharmacology; Blotting, Western; Cell Line, Tumor; Cell Survival; Flavonoids/isolation & purification; Flavonoids/pharmacology; Humans; Methanol/chemistry; Moraceae/chemistry; Neuroblastoma/pathology; Neuroprotective Agents/isolation & purification; Nuclear Receptor Subfamily 4, Group A, Member 2/genetics; Plant Extracts/pharmacology; RNA, Messenger/genetics; RNA, Messenger/metabolism; Reverse Transcriptase Polymerase Chain Reaction; alpha-Synuclein/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dopamine / Gene Expression Regulation, Neoplastic / Cell Death / Neuroprotective Agents / Alpha-Synuclein / Nuclear Receptor Subfamily 4, Group A, Member 2 Limits: Humans Language: En Journal: Phytother Res Journal subject: TERAPIAS COMPLEMENTARES Year: 2012 Document type: Article Country of publication: United kingdom

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