Branched &#945;-(1,4) glucans from Lentinula edodes (L10) in combination with radiation enhance cytotoxic effect on human lung adenocarcinoma through the Toll-like receptor 4 mediated induction of THP-1 differentiation/activation.

Lo, Tiffany Chien-Ting; Hsu, Feng-Ming; Chang, C Allen; Cheng, Jason Chia-Hsein

Branched α-(1,4) glucans from Lentinula edodes (L10) in combination with radiation enhance cytotoxic effect on human lung adenocarcinoma through the Toll-like receptor 4 mediated induction of THP-1 differentiation/activation.

Lo, Tiffany Chien-Ting; Hsu, Feng-Ming; Chang, C Allen; Cheng, Jason Chia-Hsein.

Affiliation

Lo TC; Graduate Institute of Oncology, National Taiwan University College of Medicine, Taipei, Taiwan.

J Agric Food Chem ; 59(22): 11997-2005, 2011 Nov 23.

Article in En | MEDLINE | ID: mdl-21978170

Subject(s)

Adenocarcinoma/immunology; Cell Differentiation/drug effects; Glucans/pharmacology; Lung Neoplasms/immunology; Monocytes/cytology; Shiitake Mushrooms/chemistry; Toll-Like Receptor 4/immunology; Adenocarcinoma/drug therapy; Adenocarcinoma/genetics; Adenocarcinoma/radiotherapy; Adenocarcinoma of Lung; Cell Differentiation/radiation effects; Cell Line; Glucans/chemistry; Humans; Lung Neoplasms/drug therapy; Lung Neoplasms/genetics; Lung Neoplasms/radiotherapy; Molecular Weight; Monocytes/drug effects; Monocytes/immunology; Monocytes/radiation effects; Radiation Tolerance/drug effects; Toll-Like Receptor 4/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Monocytes / Adenocarcinoma / Cell Differentiation / Shiitake Mushrooms / Toll-Like Receptor 4 / Glucans / Lung Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Agric Food Chem Year: 2011 Document type: Article Affiliation country: Taiwan Country of publication: United States

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