Population pharmacokinetics and maximum a posteriori probability Bayesian estimator of abacavir: application of individualized therapy in HIV-infected infants and toddlers.

Zhao, Wei; Cella, Massimo; Della Pasqua, Oscar; Burger, David; Jacqz-Aigrain, Evelyne

Zhao, Wei; Cella, Massimo; Della Pasqua, Oscar; Burger, David; Jacqz-Aigrain, Evelyne.

Affiliation

Zhao W; Department of Pediatric Pharmacology and Pharmacogenetics, Hôpital Robert Debré, Université Paris VII, 48 Boulevard Sérurier, Paris Cedex 19, France.

Br J Clin Pharmacol ; 73(4): 641-50, 2012 Apr.

Article in En | MEDLINE | ID: mdl-21988586

Subject(s)

Anti-HIV Agents/pharmacokinetics; Dideoxynucleosides/pharmacokinetics; HIV Infections/metabolism; Area Under Curve; Bayes Theorem; Body Weight; Child, Preschool; Dose-Response Relationship, Drug; Drug Dosage Calculations; Female; HIV Infections/drug therapy; Humans; Infant; Male; Models, Biological

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dideoxynucleosides / HIV Infections / Anti-HIV Agents Type of study: Prognostic_studies Limits: Child, preschool / Female / Humans / Infant / Male Language: En Journal: Br J Clin Pharmacol Year: 2012 Document type: Article Affiliation country: France Country of publication: United kingdom

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