Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease.

Tamura, Takuya; Sone, Masaki; Iwatsubo, Takeshi; Tagawa, Kazuhiko; Wanker, Erich E; Okazawa, Hitoshi

Tamura, Takuya; Sone, Masaki; Iwatsubo, Takeshi; Tagawa, Kazuhiko; Wanker, Erich E; Okazawa, Hitoshi.

Affiliation

Tamura T; Department of Neuropathology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.

PLoS One ; 6(11): e27408, 2011.

Article in En | MEDLINE | ID: mdl-22096569

Subject(s)

Antigens, Nuclear/metabolism; DNA-Binding Proteins/metabolism; Huntington Disease/metabolism; Huntington Disease/therapy; Neurons/pathology; Animals; Antigens, Nuclear/genetics; DNA Damage; DNA-Binding Proteins/genetics; Disease Models, Animal; Drosophila; Drosophila Proteins; Huntingtin Protein; Huntington Disease/genetics; Ku Autoantigen; Locomotion/genetics; Locomotion/physiology; Microtubule-Associated Proteins/genetics; Microtubule-Associated Proteins/metabolism; Mutation; Neurons/metabolism; RNA, Small Interfering

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Huntington Disease / Antigens, Nuclear / DNA-Binding Proteins / Neurons Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2011 Document type: Article Affiliation country: Japan Country of publication: United States

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