Low cytomegalovirus-specific T-cell counts at reactivation are associated with progression to high-level viremia or disease in seropositive recipients of hematopoietic cell grafts from seropositive but not seronegative donors.

Hoegh-Petersen, Mette; Roa, Lina; Liu, Yiping; Zhou, Feng; Ugarte-Torres, Alejandra; Louie, Polly; Fonseca, Kevin; Khan, Faisal; Russell, James A; Storek, Jan

Hoegh-Petersen, Mette; Roa, Lina; Liu, Yiping; Zhou, Feng; Ugarte-Torres, Alejandra; Louie, Polly; Fonseca, Kevin; Khan, Faisal; Russell, James A; Storek, Jan.

Affiliation

Hoegh-Petersen M; Department of Medicine, University of Calgary, Calgary, Alberta, Canada. mhoeghpe@ucalgary.ca

Cytotherapy ; 14(2): 194-204, 2012 Feb.

Article in En | MEDLINE | ID: mdl-22149135

Subject(s)

CD4-Positive T-Lymphocytes/immunology; CD4-Positive T-Lymphocytes/virology; Cytomegalovirus Infections/immunology; Cytomegalovirus Infections/virology; Hematopoietic Stem Cell Transplantation/adverse effects; Viremia/pathology; Adult; Cytomegalovirus/immunology; Cytomegalovirus/pathogenicity; Disease Progression; Ganciclovir/therapeutic use; Hematopoietic Stem Cell Transplantation/methods; Humans; Interferon-gamma/immunology; Interferon-gamma/metabolism; Lymphocyte Count; Middle Aged; Tissue Donors; Virus Activation/immunology; Virus Latency

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viremia / CD4-Positive T-Lymphocytes / Cytomegalovirus Infections / Hematopoietic Stem Cell Transplantation Type of study: Prognostic_studies / Risk_factors_studies Limits: Adult / Humans / Middle aged Language: En Journal: Cytotherapy Journal subject: TERAPEUTICA Year: 2012 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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