Relationships between the islets blood flow, nitric oxide, insulin, and cytosolic calcium in rat pancreatic islets: effects of DPP-IV inhibitor vildagliptin.

Akarte, Atul Sureshrao; Srinivasan, B P; Gandhi, Sonia

Akarte, Atul Sureshrao; Srinivasan, B P; Gandhi, Sonia.

Affiliation

Akarte AS; Delhi Institute of Pharmaceutical Sciences and Research, Pushp Vihar, Sector-3, MB Road, New Delhi 110017, India. atul_akarte123@rediffmail.com

Eur J Pharm Sci ; 45(5): 546-51, 2012 Apr 11.

Article in En | MEDLINE | ID: mdl-22155545

Subject(s)

Adamantane/analogs & derivatives; Calcium/metabolism; Dipeptidyl-Peptidase IV Inhibitors/pharmacology; Insulin-Secreting Cells/drug effects; Insulin/blood; Nitric Oxide/metabolism; Nitriles/pharmacology; Pyrrolidines/pharmacology; Regional Blood Flow/drug effects; Adamantane/pharmacology; Animals; Blood Glucose/drug effects; Cardiac Output/drug effects; Cytokines/metabolism; Cytosol/drug effects; Cytosol/metabolism; Diabetes Mellitus, Experimental/drug therapy; Diabetes Mellitus, Experimental/metabolism; Glucose/metabolism; Hemodynamics/drug effects; Insulin/metabolism; Insulin-Secreting Cells/metabolism; Peroxynitrous Acid/metabolism; Rats; Rats, Wistar; Vildagliptin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolidines / Regional Blood Flow / Adamantane / Calcium / Insulin-Secreting Cells / Dipeptidyl-Peptidase IV Inhibitors / Insulin / Nitric Oxide / Nitriles Limits: Animals Language: En Journal: Eur J Pharm Sci Journal subject: FARMACIA / FARMACOLOGIA / QUIMICA Year: 2012 Document type: Article Affiliation country: India Country of publication: Netherlands

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