DM-1, sodium 4-[5-(4-hydroxy-3-methoxyphenyl)-3-oxo-penta-1,4-dienyl]-2-methoxy-phenolate: a curcumin analog with a synergic effect in combination with paclitaxel in breast cancer treatment.

Faião-Flores, Fernanda; Suarez, José Agustín Quincoces; Pardi, Paulo Celso; Maria, Durvanei Augusto

Faião-Flores, Fernanda; Suarez, José Agustín Quincoces; Pardi, Paulo Celso; Maria, Durvanei Augusto.

Affiliation

Faião-Flores F; Laboratory of Biochemistry and Biophysics, Butantan Institute, São Paulo, Brazil. fernandafaiao@usp.br

Tumour Biol ; 33(3): 775-85, 2012 Jun.

Article in En | MEDLINE | ID: mdl-22194218

Subject(s)

Adenocarcinoma/drug therapy; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Guaiacol/analogs & derivatives; Ketones/therapeutic use; Mammary Neoplasms, Experimental/drug therapy; Adenocarcinoma/mortality; Animals; Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/pharmacology; Apoptosis/drug effects; Caspase 3/metabolism; Cell Proliferation/drug effects; Female; Guaiacol/administration & dosage; Guaiacol/pharmacology; Guaiacol/therapeutic use; Ketones/administration & dosage; Ketones/pharmacology; Mammary Neoplasms, Experimental/mortality; Mammary Neoplasms, Experimental/pathology; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Paclitaxel/administration & dosage; Survival Analysis; Tumor Burden/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Adenocarcinoma / Antineoplastic Combined Chemotherapy Protocols / Guaiacol / Ketones / Mammary Neoplasms, Experimental Limits: Animals Language: En Journal: Tumour Biol Journal subject: NEOPLASIAS Year: 2012 Document type: Article Affiliation country: Brazil Country of publication: Netherlands

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