Heat shock transcription factor Hsf1 is involved in tumor progression via regulation of hypoxia-inducible factor 1 and RNA-binding protein HuR.

Gabai, Vladimir L; Meng, Le; Kim, Geunwon; Mills, Teresa A; Benjamin, Ivor J; Sherman, Michael Y

Gabai, Vladimir L; Meng, Le; Kim, Geunwon; Mills, Teresa A; Benjamin, Ivor J; Sherman, Michael Y.

Affiliation

Gabai VL; Department of Biochemistry, Boston University Medical School, Boston, Massachusetts, USA. Gabai@bu.edu

Mol Cell Biol ; 32(5): 929-40, 2012 Mar.

Article in En | MEDLINE | ID: mdl-22215620

Subject(s)

Cell Transformation, Neoplastic; DNA-Binding Proteins/genetics; Hypoxia-Inducible Factor 1/genetics; Neoplasms, Experimental; RNA-Binding Proteins; Transcription Factors/genetics; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic/genetics; Cellular Senescence/genetics; DNA-Binding Proteins/metabolism; Female; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Heat Shock Transcription Factors; Heat-Shock Proteins/genetics; Heat-Shock Proteins/metabolism; Humans; Hypoxia-Inducible Factor 1/metabolism; Mice; Mice, Knockout; Neoplasm Transplantation; Neoplasms, Experimental/blood supply; Neoplasms, Experimental/genetics; Neoplasms, Experimental/pathology; Neovascularization, Pathologic/genetics; RNA-Binding Proteins/genetics; RNA-Binding Proteins/metabolism; Transcription Factors/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Cell Transformation, Neoplastic / RNA-Binding Proteins / DNA-Binding Proteins / Hypoxia-Inducible Factor 1 / Neoplasms, Experimental Limits: Animals / Female / Humans Language: En Journal: Mol Cell Biol Year: 2012 Document type: Article Affiliation country: United States

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