Leptin reduces the expression and increases the phosphorylation of the negative regulators of GLUT4 traffic TBC1D1 and TBC1D4 in muscle of ob/ob mice.

Sáinz, Neira; Rodríguez, Amaia; Catalán, Victoria; Becerril, Sara; Ramírez, Beatriz; Lancha, Andoni; Burgos-Ramos, Emma; Gómez-Ambrosi, Javier; Frühbeck, Gema

Sáinz, Neira; Rodríguez, Amaia; Catalán, Victoria; Becerril, Sara; Ramírez, Beatriz; Lancha, Andoni; Burgos-Ramos, Emma; Gómez-Ambrosi, Javier; Frühbeck, Gema.

Affiliation

Sáinz N; Metabolic Research Laboratory, Universidad de Navarra, Pamplona, Spain.

PLoS One ; 7(1): e29389, 2012.

Article in En | MEDLINE | ID: mdl-22253718

Subject(s)

GTPase-Activating Proteins/genetics; Gene Expression Regulation/drug effects; Glucose Transporter Type 4/metabolism; Leptin/pharmacology; Muscle, Skeletal/drug effects; Muscle, Skeletal/metabolism; Nuclear Proteins/genetics; Animals; GTPase-Activating Proteins/immunology; GTPase-Activating Proteins/metabolism; Glucose Transporter Type 4/genetics; Intracellular Space/drug effects; Intracellular Space/metabolism; Leptin/administration & dosage; Male; Metabolome/drug effects; Mice; Mice, Inbred C57BL; Mice, Obese; Nuclear Proteins/immunology; Nuclear Proteins/metabolism; Phosphorylation/drug effects; Protein Transport/drug effects; Protein Transport/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Proteins / Gene Expression Regulation / Muscle, Skeletal / Leptin / GTPase-Activating Proteins / Glucose Transporter Type 4 Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: Spain Country of publication: United States

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