Dehydrodiconiferyl alcohol isolated from Cucurbita moschata shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts.

Lee, Junghun; Kim, Donghyun; Choi, Jonghyun; Choi, Hyounjeong; Ryu, Jae-Ha; Jeong, Jinhyun; Park, Eun-Jin; Kim, Seon-Hee; Kim, Sunyoung

Lee, Junghun; Kim, Donghyun; Choi, Jonghyun; Choi, Hyounjeong; Ryu, Jae-Ha; Jeong, Jinhyun; Park, Eun-Jin; Kim, Seon-Hee; Kim, Sunyoung.

Affiliation

Lee J; Department of Biological Sciences, Seoul National University, Seoul, Korea.

J Biol Chem ; 287(12): 8839-51, 2012 Mar 16.

Article in En | MEDLINE | ID: mdl-22262865

Subject(s)

Adipogenesis/drug effects; Cucurbita/chemistry; Fibroblasts/cytology; Lipogenesis/drug effects; Obesity/metabolism; Phenols/pharmacology; Plant Extracts/pharmacology; 3T3-L1 Cells; Adipocytes/cytology; Adipocytes/drug effects; Adipocytes/metabolism; Animals; CCAAT-Enhancer-Binding Protein-alpha/genetics; CCAAT-Enhancer-Binding Protein-alpha/metabolism; Cell Differentiation/drug effects; Cells, Cultured; Fibroblasts/drug effects; Fibroblasts/metabolism; Gene Expression/drug effects; Humans; Mice; Obesity/genetics; Obesity/physiopathology; PPAR gamma/genetics; PPAR gamma/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenols / Plant Extracts / Cucurbita / Adipogenesis / Lipogenesis / Fibroblasts / Obesity Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2012 Document type: Article Country of publication: United States

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