Distinct APCs explain the cytokine bias of &#945;-galactosylceramide variants in vivo.

Bai, Li; Constantinides, Michael G; Thomas, Seddon Y; Reboulet, Rachel; Meng, Fanyong; Koentgen, Frank; Teyton, Luc; Savage, Paul B; Bendelac, Albert

Distinct APCs explain the cytokine bias of α-galactosylceramide variants in vivo.

Bai, Li; Constantinides, Michael G; Thomas, Seddon Y; Reboulet, Rachel; Meng, Fanyong; Koentgen, Frank; Teyton, Luc; Savage, Paul B; Bendelac, Albert.

Affiliation

Bai L; Committee on Immunology, Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA. baili@ustc.edu.cn

J Immunol ; 188(7): 3053-61, 2012 Apr 01.

Article in En | MEDLINE | ID: mdl-22393151

Subject(s)

Antigen-Presenting Cells/immunology; Galactosylceramides/chemistry; Interferon-gamma/metabolism; Interleukin-12/metabolism; Natural Killer T-Cells/drug effects; Animals; Antigen Presentation; Antigen-Presenting Cells/classification; Antigens, CD1d/biosynthesis; Antigens, CD1d/genetics; Antigens, CD1d/immunology; B-Lymphocytes/immunology; Cells, Cultured/drug effects; Cells, Cultured/immunology; Cells, Cultured/metabolism; Dendritic Cells/immunology; Feedback, Physiological; Galactosylceramides/immunology; Galactosylceramides/pharmacology; Gene Expression Regulation; Macrophages/immunology; Mice; Mice, Inbred C57BL; Natural Killer T-Cells/immunology; Natural Killer T-Cells/metabolism; Specific Pathogen-Free Organisms; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Interferon-gamma / Interleukin-12 / Natural Killer T-Cells / Galactosylceramides / Antigen-Presenting Cells Limits: Animals Language: En Journal: J Immunol Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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