Adenovirus-mediated dual gene expression of human interleukin-10 and hepatic growth factor exerts protective effect against CCl4-induced hepatocyte injury in rats.

Qiu, Hong; Yan, Yan; Xing, Jicheng; Zhu, Yuerong; Fang, Lin; Cao, Xiangrong; Su, Changqing

Qiu, Hong; Yan, Yan; Xing, Jicheng; Zhu, Yuerong; Fang, Lin; Cao, Xiangrong; Su, Changqing.

Affiliation

Qiu H; Department of Biochemistry, Cancer Center of PLA, Nanjing 81 Hospital, Nanjing, China.

Dig Dis Sci ; 57(7): 1857-65, 2012 Jul.

Article in En | MEDLINE | ID: mdl-22399249

Subject(s)

Adenoviridae/genetics; Carbon Tetrachloride/adverse effects; Chemical and Drug Induced Liver Injury/prevention & control; Chemical and Drug Induced Liver Injury/physiopathology; Gene Expression Regulation, Viral/physiology; Hepatocyte Growth Factor/physiology; Interleukin-10/physiology; Animals; Carbon Tetrachloride/pharmacology; Cells, Cultured; Disease Models, Animal; Genetic Vectors; Hepatocyte Growth Factor/genetics; Hepatocytes/drug effects; Hepatocytes/pathology; Hepatocytes/physiology; Humans; In Vitro Techniques; Interleukin-10/genetics; Liver/drug effects; Liver/pathology; Liver/physiology; Male; Rats; Rats, Sprague-Dawley; Transfection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carbon Tetrachloride / Gene Expression Regulation, Viral / Adenoviridae / Interleukin-10 / Hepatocyte Growth Factor / Chemical and Drug Induced Liver Injury Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Dig Dis Sci Year: 2012 Document type: Article Affiliation country: China Country of publication: United States

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