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Menopausal symptoms appear before the menopause and persist 5 years beyond: a detailed analysis of a multinational study.
Blümel, J E; Chedraui, P; Baron, G; Belzares, E; Bencosme, A; Calle, A; Danckers, L; Espinoza, M T; Flores, D; Gomez, G; Hernandez-Bueno, J A; Izaguirre, H; Leon-Leon, P; Lima, S; Mezones-Holguin, E; Monterrosa, A; Mostajo, D; Navarro, D; Ojeda, E; Onatra, W; Royer, M; Soto, E; Tserotas, K; Vallejo, M S.
Affiliation
  • Blümel JE; Institute of Biomedicine, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador.
Climacteric ; 15(6): 542-51, 2012 Dec.
Article in En | MEDLINE | ID: mdl-22530706
OBJECTIVE: Few Latin American studies have described menopausal symptoms in detail by means of a standardized assessment tool. The objective of this study was to assess the prevalence and severity of menopausal symptoms and their impact over quality of life among mid-aged Latin American women. METHOD: In this cross-sectional study, 8373 otherwise healthy women aged 40-59 years from 12 Latin American countries were asked to fill out the Menopause Rating Scale (MRS) and a questionnaire containing personal sociodemographic data. Menopause status (pre-, peri- and postmenopausal) was defined according to the criteria of the Stages of Reproductive Aging Workshop. RESULTS: Of all the studied women, 90.9% had at least one menopausal symptom (complaint) that they rated. Muscle and joint discomfort, physical and mental exhaustion and depressive mood were highly prevalent and rated as severe-very severe (scores of 3 and 4), at a higher rate than vasomotor symptoms (15.6%, 13.8% and 13.7% vs. 9.6%, respectively). Of premenopausal women (40-44 years), 77.0% reported at least one rated complaint, with 12.9% displaying MRS scores defined as severe (> 16). The latter rate increased to 26.4% in perimenopausal, 31.6% in early postmenopausal and 29.9% among late postmenopausal women. As measured with the MRS, the presence of hot flushes increased the risk of impairment of overall quality of life in both premenopausal (odds ratio 12.67; 95% confidence interval 9.53-16.83) and peri/postmenopausal women (odds ratio 9.37; 95% confidence interval 7.85-11.19). CONCLUSION: In this large, mid-aged, female Latin American series, muscle/joint discomfort and psychological symptoms were the most prevalent and severely rated menopausal symptoms. The symptoms appear early in the premenopause, significantly impair quality of life and persist 5 years beyond the menopause.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Premenopause / Postmenopause / Perimenopause / Symptom Assessment Type of study: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Aspects: Patient_preference Limits: Adult / Female / Humans / Middle aged Language: En Journal: Climacteric Journal subject: GINECOLOGIA Year: 2012 Document type: Article Affiliation country: Ecuador Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Premenopause / Postmenopause / Perimenopause / Symptom Assessment Type of study: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Aspects: Patient_preference Limits: Adult / Female / Humans / Middle aged Language: En Journal: Climacteric Journal subject: GINECOLOGIA Year: 2012 Document type: Article Affiliation country: Ecuador Country of publication: United kingdom