Adult-onset focal expression of mutated human tau in the hippocampus impairs spatial working memory of rats.

Mustroph, Martina L; King, Michael A; Klein, Ronald L; Ramirez, Julio J

Mustroph, Martina L; King, Michael A; Klein, Ronald L; Ramirez, Julio J.

Affiliation

Mustroph ML; Department of Psychology and Neuroscience Program, Davidson College, Davidson, NC 28035, USA.

Behav Brain Res ; 233(1): 141-8, 2012 Jul 15.

Article in En | MEDLINE | ID: mdl-22561128

Subject(s)

Hippocampus/pathology; Memory Disorders/pathology; Memory, Short-Term/physiology; Mutation/genetics; Space Perception/physiology; tau Proteins/metabolism; Analysis of Variance; Animals; Cell Death; Disease Models, Animal; Genetic Vectors/physiology; Glial Fibrillary Acidic Protein/metabolism; Green Fluorescent Proteins; Hippocampus/metabolism; Humans; Male; Memory Disorders/etiology; Neurofibrillary Tangles/pathology; Neurofilament Proteins/metabolism; Rats; Rats, Sprague-Dawley; Tauopathies/complications; Tauopathies/genetics; tau Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Space Perception / Tau Proteins / Hippocampus / Memory Disorders / Memory, Short-Term / Mutation Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Behav Brain Res Year: 2012 Document type: Article Affiliation country: United States Country of publication: Netherlands

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