Direct renin inhibition exerts an anti-hypertrophic effect associated with improved mitochondrial function in post-infarction heart failure in diabetic rats.

Parodi-Rullan, Rebecca; Barreto-Torres, Giselle; Ruiz, Louis; Casasnovas, José; Javadov, Sabzali

Parodi-Rullan, Rebecca; Barreto-Torres, Giselle; Ruiz, Louis; Casasnovas, José; Javadov, Sabzali.

Affiliation

Parodi-Rullan R; Department of Physiology, School of Medicine, University of Puerto Rico, San Juan, PR, USA.

Cell Physiol Biochem ; 29(5-6): 841-50, 2012.

Article in En | MEDLINE | ID: mdl-22613984

Subject(s)

Diabetes Mellitus, Experimental/physiopathology; Heart Failure/physiopathology; Mitochondria, Heart/physiology; Myocardial Infarction/complications; Renin/antagonists & inhibitors; Amides/therapeutic use; Animals; Blotting, Western; Echocardiography; Electrophoresis, Polyacrylamide Gel; Fumarates/therapeutic use; Heart Failure/diagnostic imaging; Heart Failure/drug therapy; Heart Failure/etiology; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Renin / Diabetes Mellitus, Experimental / Heart Failure / Mitochondria, Heart / Myocardial Infarction Type of study: Etiology_studies / Risk_factors_studies Limits: Animals Language: En Journal: Cell Physiol Biochem Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2012 Document type: Article Affiliation country: United States Country of publication: Germany

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