Deoxyschizandrin isolated from the fruits of Schisandra chinensis ameliorates Aß1â42-induced memory impairment in mice.

Hu, Di; Li, Changxia; Han, Na; Miao, Lijing; Wang, Dong; Liu, Zhihui; Wang, Hua; Yin, Jun

Deoxyschizandrin isolated from the fruits of Schisandra chinensis ameliorates Aß1â42-induced memory impairment in mice.

Hu, Di; Li, Changxia; Han, Na; Miao, Lijing; Wang, Dong; Liu, Zhihui; Wang, Hua; Yin, Jun.

Affiliation

Hu D; Department and Utilization Key Laboratory of Northeast Plant Materials, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.

Planta Med ; 78(12): 1332-6, 2012 Aug.

Article in En | MEDLINE | ID: mdl-22773410

Subject(s)

Antioxidants/pharmacology; Cyclooctanes/pharmacology; Drugs, Chinese Herbal/pharmacology; Lignans/pharmacology; Memory Disorders/drug therapy; Polycyclic Compounds/pharmacology; Schisandra/chemistry; Alzheimer Disease/drug therapy; Amyloid beta-Peptides; Animals; Cerebral Cortex/metabolism; Cyclooctanes/isolation & purification; Fruit/chemistry; Glutathione/metabolism; Glutathione Peroxidase/metabolism; Hippocampus/metabolism; Lignans/isolation & purification; Male; Malondialdehyde/metabolism; Maze Learning/drug effects; Memory Disorders/chemically induced; Memory Disorders/metabolism; Mice; Polycyclic Compounds/isolation & purification; Superoxide Dismutase/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polycyclic Compounds / Drugs, Chinese Herbal / Lignans / Schisandra / Cyclooctanes / Memory Disorders / Antioxidants Limits: Animals Language: En Journal: Planta Med Year: 2012 Document type: Article Affiliation country: China Country of publication: Germany

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