Functional tumor infiltrating TH1 and TH2 effectors in large early-stage cervical cancer are suppressed by regulatory T cells.

Adurthi, Sreenivas; Mukherjee, Geetashree; Krishnamurthy, H; Sudhir, Krishna; Bafna, Uttamchand D; Umadevi, Kswamy; Jayshree, Rudrapatna Subramanyam

Adurthi, Sreenivas; Mukherjee, Geetashree; Krishnamurthy, H; Sudhir, Krishna; Bafna, Uttamchand D; Umadevi, Kswamy; Jayshree, Rudrapatna Subramanyam.

Affiliation

Adurthi S; Department of Microbiology, Kidwai Memorial Institute of Oncology, Bangalore, India.

Int J Gynecol Cancer ; 22(7): 1130-7, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22872166

Subject(s)

Carcinoma, Squamous Cell/immunology; Lymphocytes, Tumor-Infiltrating/immunology; T-Lymphocytes, Regulatory/immunology; Th1 Cells/immunology; Th2 Cells/immunology; Uterine Cervical Neoplasms/immunology; Carcinoma, Squamous Cell/metabolism; Carcinoma, Squamous Cell/pathology; Cytokines/metabolism; Female; Flow Cytometry; Humans; Immune Tolerance; Interferon-gamma/metabolism; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating/metabolism; Lymphocytes, Tumor-Infiltrating/pathology; Neoplasm Staging; T-Lymphocytes, Regulatory/metabolism; T-Lymphocytes, Regulatory/pathology; Th1 Cells/metabolism; Th1 Cells/pathology; Th2 Cells/metabolism; Th2 Cells/pathology; Uterine Cervical Neoplasms/metabolism; Uterine Cervical Neoplasms/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Uterine Cervical Neoplasms / Lymphocytes, Tumor-Infiltrating / T-Lymphocytes, Regulatory / Th2 Cells / Th1 Cells Limits: Female / Humans Language: En Journal: Int J Gynecol Cancer Journal subject: GINECOLOGIA / NEOPLASIAS Year: 2012 Document type: Article Affiliation country: India Country of publication: United kingdom

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