Discovery and biosynthesis of phosphonate and phosphinate natural products.

Peck, Spencer C; Gao, Jiangtao; van der Donk, Wilfred A

Peck, Spencer C; Gao, Jiangtao; van der Donk, Wilfred A.

Affiliation

Peck SC; Department of Chemistry and the Howard Hughes Medical Institute, Urbana, Illinois, USA.

Methods Enzymol ; 516: 101-23, 2012.

Article in En | MEDLINE | ID: mdl-23034226

Subject(s)

Biological Products/metabolism; Organophosphonates/metabolism; Phosphinic Acids/metabolism; Streptomyces/chemistry; Bacterial Proteins/chemistry; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Biological Products/chemistry; Biological Products/isolation & purification; Biosynthetic Pathways; Chromatography, Liquid; Drug Discovery; Kinetics; Magnetic Resonance Spectroscopy; Organophosphonates/chemistry; Organophosphonates/isolation & purification; Phosphinic Acids/chemistry; Phosphinic Acids/isolation & purification; Spectroscopy, Fourier Transform Infrared; Streptomyces/enzymology; Streptomyces/genetics; Substrate Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphinic Acids / Streptomyces / Biological Products / Organophosphonates Language: En Journal: Methods Enzymol Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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