Membrane vesicle ABC transporter assays for drug safety assessment.

van Staden, Carlo J; Morgan, Ryan E; Ramachandran, Bharath; Chen, Yuan; Lee, Paul H; Hamadeh, Hisham K

van Staden, Carlo J; Morgan, Ryan E; Ramachandran, Bharath; Chen, Yuan; Lee, Paul H; Hamadeh, Hisham K.

Affiliation

van Staden CJ; Amgen, Inc., Thousand Oaks, California, USA.

Curr Protoc Toxicol ; Chapter 23: Unit 23.5, 2012 Nov.

Article in En | MEDLINE | ID: mdl-23169270

Subject(s)

ATP-Binding Cassette Transporters/physiology; Biological Assay/methods; Transport Vesicles/physiology; Cell Membrane; Drug Evaluation, Preclinical; Hepatocytes/drug effects; Hepatocytes/metabolism; Linear Models; Scintillation Counting

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Assay / ATP-Binding Cassette Transporters / Transport Vesicles Language: En Journal: Curr Protoc Toxicol Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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