Drug resistance to chlorambucil in murine B-cell leukemic cells is overcome by its conjugation to a targeting peptide.

Gellerman, Gary; Baskin, Sophia; Galia, Luboshits; Gilad, Yosef; Firer, Michael A

Gellerman, Gary; Baskin, Sophia; Galia, Luboshits; Gilad, Yosef; Firer, Michael A.

Affiliation

Gellerman G; Department of Biological Chemistry, Ariel University Center, Ariel, Israel.

Anticancer Drugs ; 24(2): 112-9, 2013 Feb.

Article in En | MEDLINE | ID: mdl-23187462

Subject(s)

Chlorambucil/pharmacology; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy; Peptides/pharmacology; Animals; Cell Line, Tumor; Chlorambucil/chemistry; Drug Carriers/chemistry; Drug Delivery Systems/methods; Drug Resistance, Neoplasm/drug effects; Female; Leukemia, Lymphocytic, Chronic, B-Cell/metabolism; Mice; Mice, Inbred BALB C; Peptides/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Leukemia, Lymphocytic, Chronic, B-Cell / Chlorambucil Limits: Animals Language: En Journal: Anticancer Drugs Journal subject: ANTINEOPLASICOS Year: 2013 Document type: Article Affiliation country: Israel Country of publication: United kingdom

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