[Effect of shRNA-mediated silencing of CTGF and TIMP-1 on mRNA expression of CTGF, TIMP-1, and PC I and secretion of extracellular matrix in rat hepatic stellate cells].

Jiang, Yu-feng; Sun, Hua-li; Zhang, Jian-jun; Huang, Fei; Liu, Jia-qun

Jiang, Yu-feng; Sun, Hua-li; Zhang, Jian-jun; Huang, Fei; Liu, Jia-qun.

Affiliation

Jiang YF; Department of Infectious Diseases, the Affiliated Hospital of Luzhou Medical College, Lu zhou Sichuan, China.

Zhonghua Gan Zang Bing Za Zhi ; 20(8): 576-80, 2012 Aug.

Article in Zh | MEDLINE | ID: mdl-23207149

Subject(s)

Connective Tissue Growth Factor/metabolism; Extracellular Matrix/metabolism; Hepatic Stellate Cells/metabolism; Liver Cirrhosis/pathology; RNA, Small Interfering/genetics; Tissue Inhibitor of Metalloproteinase-1/metabolism; Animals; Cells, Cultured; Collagen Type I/genetics; Collagen Type I/metabolism; Connective Tissue Growth Factor/genetics; Down-Regulation; Gene Expression Regulation; Gene Silencing; Hepatic Stellate Cells/drug effects; Hyaluronic Acid/metabolism; Laminin/metabolism; Liver Cirrhosis/metabolism; Polymerase Chain Reaction; RNA, Messenger/genetics; RNA, Messenger/metabolism; Rats; Tissue Inhibitor of Metalloproteinase-1/genetics; Transfection; Transforming Growth Factor beta/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tissue Inhibitor of Metalloproteinase-1 / RNA, Small Interfering / Extracellular Matrix / Hepatic Stellate Cells / Connective Tissue Growth Factor / Liver Cirrhosis Limits: Animals Language: Zh Journal: Zhonghua Gan Zang Bing Za Zhi Journal subject: GASTROENTEROLOGIA Year: 2012 Document type: Article Affiliation country: China Country of publication: China

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