Bruton tyrosine kinase inhibitor ibrutinib (PCI-32765).

Burger, Jan A; Buggy, Joseph J

Burger, Jan A; Buggy, Joseph J.

Affiliation

Burger JA; Department of Leukemia, The University of Texas M. D. Anderson Cancer Center , Houston, TX , USA.

Leuk Lymphoma ; 54(11): 2385-91, 2013 Nov.

Article in En | MEDLINE | ID: mdl-23425038

Subject(s)

Protein Kinase Inhibitors/therapeutic use; Protein-Tyrosine Kinases/antagonists & inhibitors; Pyrazoles/therapeutic use; Pyrimidines/therapeutic use; Adenine/analogs & derivatives; Agammaglobulinaemia Tyrosine Kinase; Animals; Autoimmune Diseases/drug therapy; Autoimmune Diseases/metabolism; B-Lymphocytes/metabolism; B-Lymphocytes/pathology; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Humans; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy; Leukemia, Lymphocytic, Chronic, B-Cell/metabolism; Lymphoma, Mantle-Cell/drug therapy; Lymphoma, Mantle-Cell/metabolism; Piperidines; Protein Kinase Inhibitors/chemistry; Protein Kinase Inhibitors/pharmacology; Pyrazoles/chemistry; Pyrazoles/pharmacology; Pyrimidines/chemistry; Pyrimidines/pharmacology; Receptors, Antigen, B-Cell/metabolism; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyrimidines / Protein-Tyrosine Kinases / Protein Kinase Inhibitors Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Leuk Lymphoma Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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