The immature dentate gyrus represents a shared phenotype of mouse models of epilepsy and psychiatric disease.

Shin, Rick; Kobayashi, Katsunori; Hagihara, Hideo; Kogan, Jeffrey H; Miyake, Shinichi; Tajinda, Katsunori; Walton, Noah M; Gross, Adam K; Heusner, Carrie L; Chen, Qian; Tamura, Kouichi; Miyakawa, Tsuyoshi; Matsumoto, Mitsuyuki

Shin, Rick; Kobayashi, Katsunori; Hagihara, Hideo; Kogan, Jeffrey H; Miyake, Shinichi; Tajinda, Katsunori; Walton, Noah M; Gross, Adam K; Heusner, Carrie L; Chen, Qian; Tamura, Kouichi; Miyakawa, Tsuyoshi; Matsumoto, Mitsuyuki.

Affiliation

Shin R; CNS, Astellas Research Institute of America LLC, Skokie, IL, USA.

Bipolar Disord ; 15(4): 405-21, 2013 Jun.

Article in En | MEDLINE | ID: mdl-23560889

Subject(s)

Behavioral Symptoms; Bipolar Disorder; Calbindin 2/metabolism; Dentate Gyrus; Epilepsy; Schizophrenia; Animals; Behavioral Symptoms/metabolism; Behavioral Symptoms/physiopathology; Biomarkers/metabolism; Bipolar Disorder/metabolism; Bipolar Disorder/pathology; Bipolar Disorder/physiopathology; Bipolar Disorder/psychology; Dentate Gyrus/growth & development; Dentate Gyrus/metabolism; Dentate Gyrus/pathology; Disease Models, Animal; Electrophysiological Phenomena; Epilepsy/metabolism; Epilepsy/pathology; Epilepsy/physiopathology; Epilepsy/psychology; Mice; Muscarinic Agonists/pharmacology; Pilocarpine/pharmacology; Schizophrenia/metabolism; Schizophrenia/pathology; Schizophrenia/physiopathology

Key words

bipolar disorder; calbindin; calcium/calmodulin-dependent protein kinase II alpha; calretinin; dentate gyrus; doublecortin; neuronal immaturity; pilocarpine; schizophrenia; seizures

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Behavioral Symptoms / Bipolar Disorder / Dentate Gyrus / Epilepsy / Calbindin 2 Limits: Animals Language: En Journal: Bipolar Disord Journal subject: PSIQUIATRIA Year: 2013 Document type: Article Affiliation country: United States Country of publication: Denmark

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google